Macula Risk® PGx AMD Genetic testing

 

What is Macula Risk PGx?

Macula Risk PGx is a combined prognostic and pharmacogenetic DNA test designed to determine a patient's risk of progression to advanced Age-related Macular Degeneration (AMD) and aid in the selection of appropriate eye vitamin therapies based on his or her individual genetic risk profile.

DNA Test Components

Advanced AMD Prognosis

Macula Risk PGx predicts a patient's risk of progression to advanced AMD with vision loss within 2, 5 and 10 years.

Validated risk determinations of two large and independent populations show test sensitivity and specificity each greater than 80% and a 10-year predictive accuracy of 89.5%1.

Genotype-Directed Eye Vitamin Therapy

The Vita Risk™ pharmacogenetic result within the Macula Risk PGx test supports the selection of appropriate eye vitamin therapies for a patient based on their combined genotype at the CFH and ARMS2 loci. A pharmacogenetic analysis of AREDS concluded that 49% of patients with moderate disease in at least one eye would derive greater benefit from a treatment regimen other than the AREDS formulation2.

Genotype Therapy



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Macula Risk






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